Detalhe da pesquisa
1.
Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models.
J Hepatol
; 78(4): 717-730, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36634821
2.
Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice.
Gastroenterology
; 158(6): 1762-1775.e9, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001321
3.
Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection.
J Infect Dis
; 221(9): 1448-1461, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31875228
4.
Amino Acid Substitutions within HLA-B*27-Restricted T Cell Epitopes Prevent Recognition by Hepatitis Delta Virus-Specific CD8+ T Cells.
J Virol
; 92(13)2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29669837
5.
Low hepatitis B virus-specific T-cell response in males correlates with high regulatory T-cell numbers in murine models.
Hepatology
; 66(1): 69-83, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28295453
6.
Polarization of Monocytic Myeloid-Derived Suppressor Cells by Hepatitis B Surface Antigen Is Mediated via ERK/IL-6/STAT3 Signaling Feedback and Restrains the Activation of T Cells in Chronic Hepatitis B Virus Infection.
J Immunol
; 195(10): 4873-83, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416274
7.
Novel Woodchuck Hepatitis Virus (WHV) transgene mouse models show sex-dependent WHV replicative activity and development of spontaneous immune responses to WHV proteins.
J Virol
; 88(3): 1573-81, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24257601
8.
Combination of DNA prime--adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model.
PLoS Pathog
; 9(6): e1003391, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23785279
9.
Therapeutic vaccination and immunomodulation in the treatment of chronic hepatitis B: preclinical studies in the woodchuck.
Med Microbiol Immunol
; 204(1): 103-14, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25535101
10.
Enhancement of HCV polytope DNA vaccine efficacy by fusion to an N-terminal fragment of heat shock protein gp96.
Arch Virol
; 160(1): 141-52, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25348271
11.
Introducing adjuvant-loaded particulate hepatitis B core antigen as an alternative therapeutic hepatitis B vaccine component.
JHEP Rep
; 6(4): 100997, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38425450
12.
CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells.
Front Immunol
; 15: 1340619, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38711498
13.
DNA prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model.
J Virol
; 86(17): 9297-310, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22718818
14.
Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice.
Vaccines (Basel)
; 11(2)2023 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36851121
15.
Efficient stabilization of therapeutic hepatitis B vaccine components by amino-acid formulation maintains its potential to break immune tolerance.
JHEP Rep
; 5(2): 100603, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36714793
16.
PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B.
Biomolecules
; 12(3)2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35327662
17.
Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B.
Front Immunol
; 12: 734246, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34691041
18.
Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection.
Vaccines (Basel)
; 9(8)2021 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34451966
19.
Intramolecular recombination enables the formation of hepatitis B virus (HBV) cccDNA in mice after HBV genome transfer using recombinant AAV vectors.
Antiviral Res
; 194: 105140, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34284057
20.
Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection.
Sci Rep
; 9(1): 10808, 2019 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31346211